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Tetrahedron letters

A one-step radical synthesis of pyrrol-2-acetic acids

JH Byers, MP Duff, GW Woo

文献索引:Byers, Jeffrey H.; Duff, Michael P.; Woo, Gregory W. Tetrahedron Letters, 2003 , vol. 44, # 36 p. 6853 - 6855

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被引用次数: 8

摘要

Pyrrol-2-acetic acids were generated following a procedure involving I-transfer radical addition of iodoacetic acids to pyrrole with spontaneous loss of HI. This procedure also allows for efficient syntheses of 2-alkyl pyrroles through subsequent thermolytic decarboxylation.