Chemistry Letters

Synthesis and unambiguous characterization of optically pure (+)-4-demethoxyadriamycin hydrochloride.

Y Kimura, M Suzuki, S Terashima

文献索引：Kimura, Yoshikazu; Suzuki, Michiyo; Terashima, Shiro Chemistry Letters, 1984 , p. 2113 - 2116

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被引用次数: 6

摘要

The title compound showing mp 226–229° C (decomp) and [α] D 20+ 190°(CH 3 OH) was synthesized by two different synthetic routes and fully characterized by its spectral properties. These studies suggested that the compound previously claimed to be 4- demethoxyadriamycin hydrochloride, mp 186–188° C (decomp), might be (+)-14-formyloxy- 4-demethoxydaunorubicin hydrochloride.