β??Carbolines from Japanese Sake and Soy Sauce: Synthesis and Biological Activity of Flazin and Yellow Substance YS (Perlolyrine)

WP Gessner, A Brossi, ME Bembenek…

文献索引：Gessner; Brossi; Bembenek; Abell Archiv der Pharmazie, 1988 ,  vol. 321,  # 2  p. 95 - 98

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被引用次数: 19

摘要

Abstract The β-carbolines flazin (1) and perlolyrine (2, substance YS) occuring in Japanese sake and soy sauce were synthesized starting with the methyl ester of L-tryptophan or tryptamine, respectively. The inhibition of the monoamine oxidases A and B by 1 and 2 were determined and compared with the inhibitory effects of harmine and harmaline.