Synthesis and biological testing of non-fluorinated analogues of levofloxacin

JL Gray, JIK Almstead, CP Gallagher, XE Hu…

文献索引：Gray, Jeffrey L.; Almstead, Ji-In K.; Gallagher, Corey P.; Hu, X. Eric; Kim, Nick K.; Taylor, Cynthia J.; Twinem, Tracy L.; Wallace, Cynthia D.; Ledoussal, Benoit Bioorganic and Medicinal Chemistry Letters, 2003 ,  vol. 13,  # 14  p. 2373 - 2375

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被引用次数: 12

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested. ... The synthesis of a series of novel quinolone antibacterials ...