Reaction of 3??(o??chlorobenzylidene)??2, 4??dioxopentanoic acid with hydroxylamine hydrochloride. Revised structure tor azeto [3, 2??d] isoxazoline

T Kurihara, M Mori, Y Sakamoto

文献索引：Kurihara,T. et al. Journal of Heterocyclic Chemistry, 1977 , vol. 14, p. 523 - 525

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被引用次数: 4

摘要

Abstract Reaction of 3-(o-ehlorobenzylidene)-2, 4-dioxopentanoic acid (1) with hydroxylamine hydro-chloride in acetic acid gave 5-(o-chlorophenyl)-3-methyl-4-(α- hydroxyimino) isoxazolineglyo-xylic acid (5) and 3-(o-chlorobenzylidene)-4-hydroxyimino-2- oxopentanoic acid (2) in 57% and 7% yields. Pyrolysis of 5 afforded 5-(o-chlorophenyl)-3- methylisoxazole-4-carbonitrile (8), cis-and trans-5-(o-chlorophenyl)-3-methylisoxazoline-4 ...