On the formation of homo??azasteroidal esters of N, N??bis (2??chloroethyl) aminobenzoic acid isomers and their antitumor activity

…, P Catsoulacos, A Papageorgiou…

文献索引：Anastasiou; Catsoulacos; Papageorgiou; Margariti Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 2 p. 367 - 374

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被引用次数: 20

摘要

Abstract The N, N-bis (2-chloroethyl) aminobenzoate isomers and the 4-methyl-3-N, N-bis (2- chloro-ethyl) aminobenzoate of 3β-hydroxy-13α-amino-13, 17-seco-5α-androstan-17-oic-13, 17-lactam, 3α-hydroxy-13α-amino-13, 17-seco-5α-androstan-17-oic-13, 17-lactam, 3α- hydroxy-13α-amino-13, 17-seco-5-androsten-17-oic-13, 17-lactam and 17β-hydroxy-3-aza- A-homo-4α-androsten-4-one, have been prepared and their biological activity evaluated ...