Discovery of 4-tert-butyl-2, 6-dimethylphenylsulfur trifluoride as a deoxofluorinating agent with high thermal stability as well as unusual resistance to aqueous …

T Umemoto, RP Singh, Y Xu…

文献索引：Umemoto, Teruo; Singh, Rajendra P.; Xu, Yong; Saito, Norimichi Journal of the American Chemical Society, 2010 , vol. 132, # 51 p. 18199 - 18205

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被引用次数: 94

摘要

Versatile, safe, shelf-stable, and easy-to-handle fluorinating agents are strongly desired in both academic and industrial arenas, since fluorinated compounds have attracted considerable interest in many areas, such as drug discovery, due to the unique effects of fluorine atoms when incorporated into molecules. This article describes the synthesis, properties, and reactivity of many substituted and thermally stable phenylsulfur trifluorides, ...