Tetrahedron Letters

Photooxygenation of 3-aryl-2-cyclohexenols: synthesis of a new series of antimalarial 1, 2, 4-trioxanes

C Singh, N Gupta, SK Puri

文献索引：Singh, Chandan; Gupta, Nitin; Puri, Sunil K. Tetrahedron Letters, 2005 , vol. 46, # 2 p. 205 - 207

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被引用次数: 43

摘要

Using easily accessible 3-aryl-2-cyclohexenols, a photooxygenation route for the preparation of bicyclic 1, 2, 4-trioxanes is reported. Several of these trioxanes have shown significant antimalarial activity against multidrug resistant Plasmodium yoelii in mice by the oral route.