Tetrahedron

N-(Diethoxyphosphoryl)-O-benzylhydroxylamine—a convenient substrate for the synthesis of N-substituted O-benzylhydroxylamines

K Błażewska, T Gajda

文献索引：Blazewska, Katarzyna; Gajda, Tadeusz Tetrahedron, 2003 , vol. 59, # 51 p. 10249 - 10254

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被引用次数: 12

摘要

Easily available N-(diethoxyphosphoryl)-O-benzylhydroxylamine was shown to be convenient, orthogonally protected substrate for regioselective N-alkylation by means of diverse halides under basic conditions (sodium hydride/tetrabutylammonium bromide). An efficient procedure for dephosphorylation of N-substituted N-(diethoxyphosphoryl)-O- benzylhydroxylamine to provide N-substituted O-benzylhydroxylamines was also ...