Anticonvulsant activity and selective inhibition of nicotinamide adenine dinucleotide??dependent oxidations by 10??(2??arylimino??3??acetylamino??4??thiazolidonyl) …
SP Singh, B Ali, TK Auyong, SS Parmar…
文献索引：Singh; Ali; Auyong; Parmar; De Boer Journal of Pharmaceutical Sciences, 1976 , vol. 65, # 3 p. 391 - 396
Abstract Several 10-(1-acetyl-4-arylthiosemicarbazido) phenothiazines and their corresponding cyclized 10-(2-arylimino-3-acetylamino-4-thiazolidonyl) phenothiazines were synthesized and characterized by their sharp melting points and elemental analyses. All compounds inhibited nicotinamide adenine dinucleotide (NAD)-dependent oxidation of pyruvate and α-ketoglutarate selectively, whereas NAD-independent oxidation of ...
