Tetrahedron Letters

Intramolecular oxidative coupling of 3-indolylarylketones with Pd (II)-catalysis under air: convenient access to indenoindolones

SK Guchhait, M Kashyap, S Kandekar

文献索引：Guchhait, Sankar K.; Kashyap, Maneesh; Kandekar, Somnath Tetrahedron Letters, 2012 , vol. 53, # 30 p. 3919 - 3922

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被引用次数: 8

摘要

A Pd-catalyzed method has been developed for the intramolecular oxidative coupling of 3- indolylarylketones under open air as terminal oxidant toward the synthesis of indeno [1, 2-b] indol-10 (5H)-ones. This reaction represents an intramolecular coupling with dual activation of C–H bonds for electron-deficient arenes, while such reactions are common for electron- rich arenes. Pd (II)-catalysis with pivalic acid as co-catalyst has been found to be crucial. ...