The reaction of a series of thioimides with phosphorus ylides, in a manner analogous to the Wittig reaction, has been examined. The resulting reaction products represent potentially valuable intermediates in tetrapyrrole pigment syntheais. In addition to the desired thio- Wittig-type coupling reaction, the presence of two competing reaction pathways, Salkylation and ondation/reduction, has been obeerved with certain substrates. These empirical ...
[Lawson, Edward C.; Santulli, Rosemary J.; Dyatkin, Alexey B.; Ballentine, Scott A.; Abraham, William M.; Rudman, Sandra; Page, Clive P.; de Garavilla, Lawrence; Damiano, Bruce P.; Kinney, William A.; Maryanoff, Bruce E. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 12 p. 4208 - 4216]
