Artificial [FeFe]??Hydrogenase: On Resin Modification of an Amino Acid to Anchor a Hexacarbonyldiiron Cluster in a Peptide Framework
…, S Shinde, GA Hamilton, HE Hartnett…
文献索引：Roy, Souvik; Shinde, Sandip; Hamilton, G. Alexander; Hartnett, Hilairy E.; Jones, Anne K. European Journal of Inorganic Chemistry, 2011 , # 7 p. 1050 - 1055
Abstract A general method for immobilization of synthetic analogues of the [FeFe]- hydrogenase in designed peptides via on resin modification of an amino acid side chain with a dithiol functional group is described. Utilizing a unique amine side chain as anchor, the dithiol unit is coupled to the peptide via formation of an amide. This dithiol unit precisely positions the two required sulfur atoms for the formation of a [(μ-SRS){Fe (CO) 3} 2] cluster ...
