Tetrahedron letters

Isoindolinones via a room temperature palladium nanoparticle-catalysed 3-component cyclative carbonylation–amination cascade

R Grigg, L Zhang, S Collard, A Keep

文献索引：Grigg, Ronald; Zhang, Lixin; Collard, Simon; Keep, Ann Tetrahedron Letters, 2003 , vol. 44, # 37 p. 6979 - 6982

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被引用次数: 48

摘要

A room temperature 3-component cascade process involving nucleophilic substitution/ carbonylation/amination, catalysed by palladium nanoparticles generated in situ from palladacycle 5, affords isoindolinones in good yields. The conversions correlate with the pKa values of the amines.