Convenient synthesis of 2-amino-1, 8-naphthyridines, building blocks for host-guest and self-assembling systems

…, TJ Murray, MH Baloga, SC Zimmerman

文献索引：Fenlon, Edward E.; Murray, Thomas J.; Baloga, Monica H.; Zimmerman, Steven C. Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6625 - 6628

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被引用次数: 58

摘要

The donor-acceptor-acceptor (DAA) arrangement of hydrogen bonding sites in 2- carboxamidonaphthyridines (eg 1) allows it to pair with guanine (2) in much the same way that cytosine does. Indeed, an HPLC bonded phase generated by covalently linking la to silicagel (R=(CH2) lo-SiMezO-silica) showed excellent retention of tri-0-acetylguanosine.'We recently quantified the strength of this interaction and found that ...