Tetrahedron Letters

Highly efficient and catalyst-free synthesis of unsymmetrical thioureas under solvent-free conditions

AZ Halimehjani, Y Pourshojaei, MR Saidi

文献索引：Halimehjani, Azim Ziyaei; Pourshojaei, Yaghoub; Saidi, Mohammad R. Tetrahedron Letters, 2009 , vol. 50, # 1 p. 32 - 34

全文：HTML全文

被引用次数: 30

摘要

A highly efficient and simple synthesis of unsymmetrical thioureas is reported based on the reaction of readily synthesized dithiocarbamates with amines, without using any catalyst under solvent-free conditions. The short reaction time, high yields, and solvent-free conditions are advantages of this method. We did not observe the formation of any symmetric disubstituted thiourea, under these reaction conditions.