Discovery of INT131: A selective PPARγ modulator that enhances insulin sensitivity

JP Taygerly, LR McGee, SM Rubenstein…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 21, # 4 p. 979 - 992

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被引用次数: 18

摘要

... Bioorganic & Medicinal Chemistry. ... 2 and 3 Despite extensive research and development of anti-diabetic therapies by the pharmaceutical industry, there ... Thus, a medicinal chemistry effort was initiated to develop SAR around this diarylsulfonamide scaffold with the goal of ...