Amidines. 3. Thioureas possessing antihypertensive activity

B Loev, PE Bender, H Bowman, A Helt…

文献索引：Loev,B. et al. Journal of Medicinal Chemistry, 1972 , vol. 15, # 10 p. 1024 - 1027

全文：HTML全文

被引用次数: 24

摘要

1024 Journal OfMedicinal Chemistry, 1972, Vol. 15, No. 10 Loev, et al. pare the cytotoxicity of 3 with BrdUrd and experiments to demonstrate the incorporation of an isotopically labeled compound 3 into the DNA of hamster cells are in progress. The effect of the hypothetical methylphosphonate diester bond (in DNA) upon the biosynthesis, enzymatic repair, and physical properties of DNA remains to be investigated. Acknowledgments. The authors ...