Darstellung und Charakterisierung von diastereomeren (4S)??3??Acetyl??2??aryl??5, 5??dimethyl??4??thiazolidincarbonsäuren

…, J Kajtár, M Kajtár, M Kajtár??Peredy

文献索引：Gyoergydeak, Zoltan; Kajtar, Judit; Kajtar, Marton; Kajtar-Peredy, Maria Liebigs Annalen der Chemie, 1990 , p. 281 - 286

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被引用次数: 7

摘要

The condensation of aromatic aldehydes 1 and D-penicillamine (2) in aqueous methanol gives (4S)-2-aryl-5, 5-dimethyl-4-thia-zolidinecarboxylic acids 3 with alternating diastereoselectivity in position 2. Acetylation of the products with acetic anhydride in pyridine or in water gives rise to (ZS, 4S)-3-acetyl-2-aryl-5, 5-dimethyl-4-thiazolidinecarboxylic acids 5. Use of a