Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus

…, J O'Meara, C Kuhn, L Constantineau-Forget…

文献索引：Decor, Anne; Grand-Maitre, Chantal; Hucke, Oliver; O'Meara, Jeff; Kuhn, Cyrille; Forget, Lea Constantineau; Brochu, Christian; Malenfant, Eric; Bertrand-Laperle, Megan; Bordeleau, Josee; Ghiro, Elise; Pesant, Marc; Fazal, Gulrez; Gorys, Vida; Little, Michael; Boucher, Colette; Bordeleau, Sylvain; Turcotte, Pascal; Guo, Tim; Garneau, Michel; Spickler, Catherine; Gauthier, Annick Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3841 - 3847

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被引用次数: 2

摘要

We describe here the design, synthesis and biological evaluation of antiviral compounds acting against human rhinovirus (HRV). A series of aminothiazoles demonstrated pan- activity against the HRV genotypes screened and productive structure–activity ...