Synthetic Communications®

Efficient Procedure for the Preparation of Oligomer-Free N α-Fmoc Amino Acids

S Nowshuddin, MNA Rao, AR Reddy

文献索引：Nowshuddin, Shaik; Rao; Reddy, A. Ram Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031

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被引用次数: 4

摘要

Abstract A two-step method is presented for the peptide-free, high-purity, and high-yield synthesis of Nα-Fmoc amino acids. The first step involves the preparation of stable dicyclohexylammonium–amino acid ionic adduct in acetone. Subsequently, the ionic