A relay strategy was employed to achieve an intermolecular ene–yne metathesis between 1, 1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene–yne metathesis gives rise to 1, 1, 3-trisubstituted-1, 3-dienes previously inaccessible by direct ene–yne metathesis methods.
