Tetrahedron letters

TEAF mediated hydroxylation of allylic bromide: A facile synthesis of 4-methoxycarbonyl-2 (5H)-furanone

I Beltaïef, R Besbes, H Amri, J Villiéras

文献索引：Beltaief, Imen; Besbes, Rafaa; Amri, Hassen; Villieras, Jean Tetrahedron Letters, 1997 , vol. 38, # 5 p. 813 - 814

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被引用次数: 27

摘要

A simple two-step synthesis of 4-methoxycarbonyl-2 (5H)-furanone consisting of formylation of dimethyl 2-(bromomethyl) fumarate, followed by acid catalysed transesterification in methanol was carried out. It led to the corresponding substituted furanone in 67% global yield.