Synthesis of 1-benzyl-6-azauracil derivatives, chlorinated in the nucleus

A Nováček, V Sedláčková, B Vondráček…

文献索引：Novacek; Sedlackova; Vondracek; et al. Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 9 p. 2203 - 2206

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摘要

Abstract Glyoxylic acid 2-benzylsemicarbazone derivatives, chlorinated in the aromatic nucleus (Ia-Id) were prepared either by reaction of glyoxylic acid semicarbazone with the corresponding benzyl chlorides or by treatment of benzylidene semicarbazide with substituted benzyl chlorides and reaction of the formed semicarbazides IIIa-IIId with glyoxylic acid. The semicarbazones Ia-Id were cyclized by heating with sodium hydroxide in ...