Organic letters

Regioselective synthesis of pyrazole triflones based on triflyl alkyne cycloadditions

H Kawai, Z Yuan, E Tokunaga, N Shibata

文献索引：Kawai, Hiroyuki; Yuan, Zhe; Tokunaga, Etsuko; Shibata, Norio Organic Letters, 2012 , vol. 14, # 20 p. 5330 - 5333,4

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被引用次数: 38

摘要

The regioselective synthesis of pyrazole triflones has been achieved by 1, 3-dipolar cycloaddition of triflyl alkynes and hydrazonoyl chloride in the presence of Hünig's base. Pyrazolo [5, 1-a] isoquinoline triflones were also regioselectively synthesized for the first time via tandem 1, 3-dipolar cycloaddition/oxidative aromatization between triflyl alkynes and C, N-cyclic azomethine imines.