Protic pyridinium ionic liquid as a green and highly efficient catalyst for the synthesis of polyhydroquinoline derivatives via Hantzsch condensation in water
The four-component Hantzsch condensation reaction of dimedone, ethyl acetoacetate, ammonium acetate and various aromatic and aliphatic aldehydes in the presence of 2- methylpyridinium trifluoromethanesulfonate ([2-MPyH] OTf) as a green and highly efficient catalyst in water affords polyhydroquinoline derivatives in good to excellent yields. This reaction has been carried out in the presence of 1mol% of [2-MPyH] OTf at room ...
[Sainani, J. B.; Shah, A. C.; Arya, V. P. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 6 p. 526 - 531]
