Aporphines. 34.(-)-2, 10, 11-Trihydroxy-Nn-propylnoraporphine, a novel dopaminergic aporphine alkaloid with anticonvulsant activity

…, B Meldrum, G Anlezark, KJ Watling

文献索引：Neumeyer; Law; Meldrum; Anlezark; Watling Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 898 - 899

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被引用次数: 15

摘要

b (NPA), R= n-propyl la (APO), R= CH, 2a (normorphothebaine), R= H; R= CH, b, R= CH,; R= n-propyl c (TNPA), R= H; R= n-propyl treatment of various forms of epilepsy dates back to 1877.'More recently, La1 and his co-worker~~-~ observed that APO antagonized extreme photosensitivity in a patient with Kufs disease and found that APO. HCl (1.24-1.5 mg sc) in 9 of 11 patients with primary corticoreticular epilepsy, in whom generalized epileptic ...