Abstract A convenient method for the synthesis of 3-acyl-1, 2-benzisoxazoles, which are unstable toward bases, is described. Base-catalyzed cyclization of 2-alkyl-and aryl-1, 3- dithian-2-yl o-chlorophenylketoximes 4a-1 gave 3-(2-alkyl-and aryl-1, 3-dithian-2-yl)-1, 2- benzisoxazoles 8a-1, which were converted into the corresponding 3-acyl-1, 2- benzisoxazoles 1a-1.
![3-(2-methyl-1,3-dithian-2-yl)benzo[d]isoxazole结构式](https://image.chemsrc.com/caspic/060/78555-71-2.png)
