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Regio-and stereo-specific synthesis of threo-3-amino-2-hydroxy-acids, novel amino-acids contained in aminopeptidase inhibitors of microbial origin

K Kato, T Saino, R Nishizawa, T Takita…

文献索引:Kato; Saino; Nishizawa; Takita; Umezawa Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 7, p. 1618 - 1621

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被引用次数: 3

摘要

-3-Amino-2-hydroxy-4-phenylbutanoic acid, a novel amino-acid contained in bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase, and-3-amino-2-hydroxy-5- methylhexanoic acid, a novel amino-acid contained in amastatin, an inhibitor of aminopeptidase A and leucine aminopeptidase, have been synthesized