Abstract An efficient preparation of fused [2, 1-b] quinazolinones has been developed utilizing polymer-supported reagents.(±)-Vasicinone was converted into its dione by oxidation with poly (4-vinylpyridiniumdichromate). An efficient method has been developed for the synthesis of (d)-and (l)-vasicinone via asymmetric reduction of pyrrolo [2, 1-b] quinazoline-3, 9-dione by employing NaBH 4/Me 3 SiCl as the reducing agent and ...
[Kamal, Ahmed; Ramana, A. Venkata; Reddy, K. Srinivasa; Ramana, K. Venkata; Hari Babu; Prasad, B. Rajendra Tetrahedron Letters, 2004 , vol. 45, # 44 p. 8187 - 8190]