Synthesis of Spiro Heterocyclic Compounds

MN Ibrahim, MF El-Messmary…

文献索引：Ibrahim, Mohamed N.; El-Messmary, Mohamed F.; Elarfi, Mohamed G.A. E-Journal of Chemistry, 2010 , vol. 7, # 1 p. 55 - 58

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被引用次数: 1

摘要

Reaction of isatin with acetophenone derivatives gave 3-hydroxy-3-phenacyl oxindole derivatives (II), dehydration of (II) gave 3-phenacylidene-2-indolinone derivatives (III). Condensation of (III) with hydrazine hydrate, phenylhydrazine and phenylthiourea afforded new spiropyrazolines (IV & V) and spiropyrimidinethione (VI) respectively. The structures of the final products were established by physical and spectral means.