2-[Bis (methylthio) methylene]-1, 3-indanedione has been shown to be a useful three carbon 1, 3-dielectrophilic synthon for the highly efficient regiospecific synthesis of a variety of indenofused five-and six-membered heterocycles via heteroaromatic annulation. The methodology has been further elaborated to the corresponding N, S-acetals leading to amino substituted heterocycles, thus providing further point of diversity in the newly ...