Tetrahedron

Stereoselective migration of sterically hindered organoboranes in cyclic and acyclic systems. A stereoselective allylic C–H activation reaction

E Hupe, D Denisenko, P Knochel

文献索引：Hupe, Eike; Denisenko, Dmitri; Knochel, Paul Tetrahedron, 2003 , vol. 59, # 46 p. 9187 - 9198

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被引用次数: 12

摘要

The diastereoselective synthesis of organic molecules is an important research field and numerous important synthetic contributions have been made in recent years. 1 It was known that organoboranes derived from disubstituted olefins by hydroboration undergo a thermal isomerization at elevated temperatures (100–160°C). 2. and 3. We have shown that cyclic 3. and 4. and acyclic 5 tetrasubstituted olefins undergo a 1,2-thermal migration under milder conditions. Furthermore, these ...