Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries

T Suzuki, Y Ota, M Ri, M Bando, A Gotoh…

文献索引：Journal of Medicinal Chemistry, , vol. 55, # 22 p. 9562 - 9575

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被引用次数: 56

摘要

... Journal of Medicinal ... Graduate School of Medical Sciences, Nagoya ... is a drug discovery approach that enables high-throughput identification of small-molecular inhibitors using a minimal number of compounds as building blocks.(20) It allows medicinal chemists to explore n ...