Organic letters

An Efficient Synthesis of the Fully Elaborated Isoindolinone Unit of Muironolide A

Q Xiao, K Young, A Zakarian

文献索引：Xiao, Qing; Young, Kyle; Zakarian, Armen Organic Letters, 2013 , vol. 15, # 13 p. 3314 - 3317

全文：HTML全文

被引用次数: 12

摘要

An efficient stereocontrolled construction of the fully substituted isoindolone subunit of muironolide A is described. The approach is centered on the intramolecular Diels–Alder reaction between the enol form of the β-keto amide and an α, β, γ, δ-unsaturated ester, followed by the installation of the cyclohexene double bond.