An Improved Synthesis of bis (p-Phenylene)-32-crown-4

DS Nagvekar, HW Gibson

文献索引：Nagvekar, Devdatt S.; Gibson, Harry W. Organic Preparations and Procedures International, 1997 , vol. 29, # 2 p. 234 - 236

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被引用次数: 3

摘要

Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 bis (p-Phenylene)-32-crown-4 (6), a hydrophobic macrocycle containing two decamethylene spacers, is a potentially important cyclic component of polyrotaxanes.'-3 Herein we report an improved, four-step synthesis of 6, relative to the previous one-step method4 (5 to 7% yield). 1, lO-bis (p-Formy1phenoxy) decane (3) was prepared in 94% ...