Tetrahedron: Asymmetry

1-Azaspiro [4.4] nonane-2, 6-dione and the separation and absolute configurations of its enantiomers

T Nagasaka, H Sato, S Saeki

文献索引：Nagasaka, Tatsuo; Sato, Hiroto; Saeki, Shin-Ichiro Tetrahedron Asymmetry, 1997 , vol. 8, # 2 p. 191 - 194

全文：HTML全文

被引用次数: 30

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Racemic 1-azaspiro[4.4]nonane-2,6-dione 1 was easily synthesized from cyclopentanone in five steps and resolved via chiral acetals into enantiomers. Cephlotaxine (−)-3 and its enantiomer (+)-3 were obtained from (−)-1 and (+)-1, respectively, according to the literature.