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Tetrahedron Letters

H-Phosphonylphosphonate triethylester: the first member of a novel family of stable bisphosphorylated compounds; its short synthesis and reactivity with aldehydes

P Bisseret, J Eustache

文献索引:Bisseret, Philippe; Eustache, Jacques Tetrahedron Letters, 2001 , vol. 42, # 48 p. 8451 - 8453

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被引用次数: 13

摘要

A short preparation of the first member (1) of the novel H-phosphonylphosphonate family is described. Its reaction with aldehydes provides a straightforward access to the hitherto almost unprecedented class of α-hydroxyphosphinylphosphonates 3 of potential value in particular in medicinal chemistry.