The Journal of organic chemistry

Asymmetric Carbamoyl Anion Additions to Chiral N-Phosphonyl Imines via the GAP Chemistry Process and Stereoselectivity Enrichments

CW Seifert, S Pindi, G Li

文献索引：Kaur, Parminder; Wever, Walter; Pindi, Suresh; Milles, Raizada; Gu, Peng; Shi, Min; Li, Guigen Green Chemistry, 2011 , vol. 13, # 5 p. 1288 - 1292

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被引用次数: 6

摘要

Carbamoyl anions were found to smoothly react with chiral N-phosphonyl imines in toluene at− 78° C to rt using LiHMDS as the base. Group-assisted purification (GAP) has been utilized to give the pure amides without using column chromatography or recrystallization.