Environmentally Benign Lewis Acid Promoted [2+ 3] Dipolar Cycloaddition Reactions of Nitrile Imines with Alkenes in Water

S Dadiboyena, AT Hamme

文献索引：Dadiboyena, Sureshbabu; Hamme II, Ashton T. European Journal of Organic Chemistry, 2013 , # 33 p. 7567 - 7574

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被引用次数: 1

摘要

Abstract Mild and environmentally benign Lewis acid promoted 1, 3-dipolar cycloaddition reactions of α-hydrazonyl chlorides with alkenes in water are reported. In the presence of Lewis acids, these α-hydrazonyl chlorides generate nitrile imines in situ, which then undergo reaction with a dipolarophile to furnish the corresponding cycloaddition product. In many cases, the required times for the completion of the Lewis acid promoted 1, 3-dipolar ...