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Chemistry of Quinoline-5, 8-diones

M Behforouz, J Haddad, W Cai…

文献索引:Behforouz, Mohammad; Haddad, Jalal; Cai, Wen; Gu, Zhengxiang Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 343 - 346

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被引用次数: 37

摘要

Room-temperature acid-catalyzed methanolysis of 7-formamido-, 7-acetamido-, or 7- isobutyramido-2-methylquinoline-5, 8-diones (3, 4, 5) gives good to excellent yields of 7- amino-2-methylquinoline-5, 8-dione (6). Simple methods for the synthesis of novel 7-amino- 6-chloro-2-methylquinoline-5, 8-dione (7), 7-alkoxy-2-methylquinoline-5, 8-diones (9-11), and quinoline quinols (12, 13) are described, and the corresponding mechanisms are ...