Tetrahedron letters

Synthesis of pyrido [2, 3, 4-kl] acridines a building block for the synthesis of pyridoacridine alkaloids

G Gellerman, A Rudi, Y Kashman

文献索引：Gellerman, Gari; Rudi, Amira; Kashman, Yoel Tetrahedron Letters, 1992 , vol. 33, # 38 p. 5577 - 5580

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被引用次数: 12

摘要

Abstract Two new syntheses have been developed for the preparation of substituted pyrido [2, 3, 4-kl] acridines. The first synthesis involves a Skraup reaction and a nitrene insertion whereas the second includes a new pyridine ring synthesis starting from a 1-amino group on acridine and taking advantage of the active 9-position of the latter heterocycle.