The Uses of Ethyl Cyanobromoacetate in Heterocyclic Synthesis: Novel Synthesis of Thiophene, Pyrazolo [3, 4d] thiazole and Thieno [2, 3d] pyridazine Derivatives

…, S El-Kousy, AM El-Torgoman

文献索引：Mohareb, Rafat Milad; El-Kousy, Salah; El-Torgoman, Abdel Monem Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 8 p. 1747 - 1757

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被引用次数: 8

摘要

Abstract The reaction of active methylene reagents Ia-Ie with phenyl isothiocyanate in basic N, N-dimethylformamide solution followed by cyclization with ethyl cyanobromoacetate II affords the acyclic thioether derivatives IVa-IVe. The use of IVa-IVe in heterocyclic synthesis was described.