Synthesis of 1-[4-(3-chloropropanoyl) phenyl]-2-phenylethanedione

I Lukáč, GK Das Mohapatra

文献索引：Lukac, Ivan; Mohapatra, Gour K. Das Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 5 p. 1085 - 1091

全文：HTML全文

被引用次数: 3

摘要

Abstract 1-[4-(3-Chloropropanoyl) phenyl]-2-phenylethanedione (I) was prepared by Friedel- Crafts acylation of (3-chloropropyl) benzene with phenylacetyl chloride, oxidation with SeO 2 of the resulting 1-[4-(3-chloropropyl) phenyl]-2-phenyl-1-ethanone (IV) to 1-[4-(3- chloropropyl) phenyl]-2-phenylethanedione (V), and subsequent transformation of its benzyl CH 2 group to carbonyl, via bromo (VI), acetoxy (VII) and hydroxy (VIII) derivatives.