Ionic liquid phase technology supported the three component synthesis of Hantzsch 1, 4-dihydropyridines and Biginelli 3, 4-dihydropyrimidin-2 (1H)-ones under …
JC Legeay, JJV Eynde, JP Bazureau
文献索引:Legeay, Jean-Christophe; Vanden Eynde, Jean Jacques; Bazureau, Jean Pierre Tetrahedron, 2005 , vol. 61, # 52 p. 12386 - 12397
A microwave dielectric heating assisted liquid phase synthesis of 1, 4-dihydropyridines, 3, 4- dihydropyrimidin-2 (1H)-ones, pyridines and polyhydroquinolines using task-specific ionic liquid as a soluble support was described. The efficiency of the ionic liquid phase organic synthesis (IoLiPOS) methodology was demonstrated by using a one-pot three component condensation. The structure of the intermediates in each step was verified routinely by ...