Identification of 1-(3, 4-dihydroxyphenylazo)-2-hydroxynaphthalene as the product of oxidation of 1-phenylazo-2-hydroxynaphthalene (Sudan I, solvent yellow 14) by …
…, E Frei, HH Schmeiser, M Wiessler
文献索引:Stiborova, Marie; Asfaw, Befekadu; Frei, Eva; Schmeiser, Heinz H.; Wiessler, Manfred Collection of Czechoslovak Chemical Communications, 1994 , vol. 59, # 12 p. 2727 - 2733
Abstract The carcinogenic azo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I, Solvent Yellow 14) is oxidized by rat liver microsomes to a number of azo-containing metabolites. One of the products of hitherto unknown structure has been shown to be identical with 1-(3, 4-dihydroxyphenylazo)-2-hydroxynaphthalene. The identification of this product completed the pattern of major products of Sudan I oxidation by microsomal cytochrome P-450.