A concise stereoselective synthesis of (−)-erycibelline

ZL Zhang, S Nakagawa, A Kato, YM Jia…

文献索引：Zhang, Zhao-Lan; Nakagawa, Shinpei; Kato, Atsushi; Jia, Yue-Mei; Hu, Xiang-Guo; Yu, Chu-Yi Organic and Biomolecular Chemistry, 2011 , vol. 9, # 22 p. 7713 - 7719

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被引用次数: 13

摘要

(−)-Erycibelline, the dihydroxynortropane alkaloid isolated from Erycibe elliptilimba Merr. et Chun., was synthesized using a cyclic nitrone as advanced intermediate, wherein the key step was the SmI2-induced intramolecular reductive coupling of cyclic nitrone with aldehyde which resulted in good yield and stereoselectivity.