Antitumor agents. 134. New shiraiachrome A and calphostin C-related perylene derivatives as cytotoxic and antiviral agents and inhibitors of protein kinase C
HK Wang, JX Xie, JJ Chang, KM Hwang…
文献索引：Wang; Xie; Chang; Hwang; Liu; Ballas; Jiang; Lee Journal of Medicinal Chemistry, 1992 , vol. 35, # 15 p. 2717 - 2721
Shiraiachrome-A and-B have been isolated from the mycelium of the Chinese bamboo fungus Shiraia bambwicola as the cytotoxic principles. A series of new perylene derivatives (7-27) related to Shiraiachrome-A and-B as well as Calphostin-C have been synthesized and evaluated for their cytotoxicity, antiviral activity, and inhibitory activity against protein kinase C. The resulta indicated that 11 and 12 are potent cytotoxic agents against HCT-8, ...
