Synthesis of 4-Sulfur-Substituted (2 S, 3 R)-3-Phenylserines by Enzymatic Resolution. Enantiopure Precursors for Thiamphenicol and Florfenicol

B Kaptein, TJGM van Dooren…

文献索引：Organic Process Research and Development, , vol. 2, # 1 p. 10 - 17

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被引用次数: 28

摘要

... Organic Chemistry & Biotechnology Section, DSM Research, PO Box 18, 6160 MD Geleen ... 14 Since most processes to thiamphenicol and florfenicol proceed via (racemic) sulfur-substituted ... and (b) sulfonation of a readily available intermediate in the chloramphenicol process. ...