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Synthesis of 1-O-silylated 3-azido-and 3-N-trifluoroacetamido-2, 3, 6-trideoxy-L-arabino and L-lyxo-hexopyranoses, convenient glycosyl donors for preparation of …

G Grynkiewicz, I Fokt, P Skibicki, T Przewloka…

文献索引:Grynkiewicz; Fokt; Skibicki; Przewloka; Szeja; Priebe Polish Journal of Chemistry, 2005 , vol. 79, # 2 p. 335 - 347

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被引用次数: 10

摘要

Résumé/Abstract Over the years our studies have been aimed at the preparation of DNA- binding agents containing L-daunosamine, L-acosamine, or their derivatives, and we have found 1-Osilylated 2-deoxy-hexopyranoses to be very valuable as synthetic intermediates and glycosyl donors. We present here efficient strategies for the synthesis and separation of 1-O-silylated 3-azido-and 3-amino-2, 3, 6-trideoxy-L-hexopyranoses and the design of ...